Frequently Asked Questions...
Serious questions about rabies, Medical professional only, no Wikipedia please?
1.) After a rabid animal bites someone, does rabies travel through the blood throughout the body? I know it travels via CNS, but what if (hypothetical) a parapalegic gets bitten on the leg and his CNS doesn't connect to the brain, could he still get infected?
2.) A.) What if rabies was air born, could the human population survive it okay? Once you get symptoms your pretty much dead, except for the milawakee protocol. and the whole world couldn't do that.
B.) Is it possible to put it into a powder? if so wouldn't it be one of the deadliest biological warfare weapons, people wouldn't even know. You could shake someones hand with rabies on it and then if they touch their face or mouth they are screwed?
ALL HYPOTHETICAL JUST CURIOUS
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Answer:
I'll answer #2 first - answer to part A is yes, because there is an effective vaccine or rabies - it's required for most pets, and can be used in humans. You could pretty easily vaccinate the entire human population if the need arose for some reason. Also, rabies is one of the cases where vaccinating after exposure is also effective, as long as it is done before any symptoms show up. In fact, that's how the handful of human rabies cases that occur each year are handled (humans don't get the vaccine because the chance of exposure is so low). Human deaths from rabies in developed countries are exceedingly rare - there might be only 1 case every few years in the US, and is invariably because for whatever reason, the infected person didn't seek treatment (in developing countries, it can be a very different story, because proper treatment is not always available).
The answer to part B (and your premise for part A) is no - the rabies virus sucks at surviving in air - it has to stay in fluid, and when it dries out, the virus quickly dies. While you could theoretically get rabies by inhaling droplets of infected saliva, it would require a very unusual scenario. You couldn't distribute it as a powder, it would have to be a spray of some sort. I think someone would notice you shaking their hand if your hand was covered in liquid, and most people would probably make a point of washing their hands before bringing it anywhere close to their face. Since it can't infect through intact skin, it would be hard to surreptitiously infect someone in that manner.
As for question 1, this is more of a guess - yes, rabies can probably travel through blood, but it doesn't stay there for long because it tries to find nerve tissue to attach to. For that reason, the blood of an infected animal isn't considered to be infectious. As far as the paraplegic goes, it's an interesting thought, but I think the person would be affected anyway. There is still nerve tissue in the leg - the virus would still infect that and replicate, and eventually dump lots of copies of itself out of the affected nerve. Even though there may be no direct neural connection to the brain, the leg is still attached to the rest of the body through the blood supply and other tissues. So, viruses could simply travel the gap by some other route, and infect nerves on the other side that DO lead to the brain.
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